NDV HN (13H3)

mouse

NDV HN 抗体 13H3 是小鼠单克隆 IgG2a，提供 100 µg/ml raised against HN of La-sota strain of Newcastle disease virus origin 推荐用于 Newcastle disease virus 来源的hemagglutinin neuraminidase ELISA检测 目前，我们还没有完成NDV HN 抗体 (13H3)的首选二抗检测试剂的鉴定。这项工作正在进行中。 Newcastle disease virus (NDV) is a negative-sense single-stranded RNA virus which causes Newcastle disease, a highly contagious zoonotic bird disease affecting many domestic and wild avian species. Transmission occurs by exposure to fecal and other excretions from infected birds and replication takes place in the cytoplasm of the host cell. NDV HN (hemagglutinin neuraminidase) is one of eight proteins encoded by the NDV genome. NDV HN is glycosylated and functions as a component of the external envelope, responsible for the binding of NDV to host cells. More specifically, NDV HN attaches to the sialic acid-containing receptors on target cells and causes an upregulation in the host cell expression of TRAIL, death receptors (DRs) and IFN-α. Once bound, the viral and cell-surface membranes fuse through a process regulated by the NDV F protein. Both NDV HN and NDV F proteins promote the infection of neighboring cells and are therefore involved in the viral infectivity and virulence of NDV.For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

IGG-免疫球蛋白G型抗体

ELISA