MAGI-2 (6F5)

mouse

抗-MAGI-2 抗体 6F5 是小鼠单克隆 IgG1 (kappa轻链)，MAGI-2抗体，规格为100 µg/ml raised against amino acids 519-628 representing partial length MAGI-2 of human origin 推荐用于 mouse, rat 和 human 来源的MAGI-2 WB, IP 和 ELISA检测 关于如何获取MAGI-2 (6F5): sc-517008的免费10 µg小样，联系我们技术服务部门 (或者您当地的代理商)了解详情。 目前，我们还没有完成MAGI-2 抗体 (6F5)的首选二抗检测试剂的鉴定。这项工作正在进行中。 MAGI-2 Antibody (6F5) is a high quality monoclonal MAGI-2 antibody (also designated MAGI2 antibody or ACVRINP1 antibody) suitable for the detection of the MAGI-2 protein of mouse, rat and human origin. MAGI-2 Antibody (6F5) is available as the non-conjugated anti-MAGI-2 antibody. The membrane-associated guanylate kinase (MAGUK) proteins are concentrated at the membrane-cytoskeletal interface where they facilitate the assembly of multiprotein complexes on the inner surface of the plasma membrane. Three protein-protein interaction modules characteristically define MAGUK related proteins: the PDZ domain, the SH3 domain and the guanylate kinase (GuK) domain. The closely related MAGUK proteins, MAGI-1, MAGI-2 and MAGI-3 (membrane associated guanylate kinase inverted-1 and 2), likewise contain the GuK domain and five PDZ domains; however, the SH3 domain is replaced with a WW domain. The transcripts of MAGI-1 are alternatively spliced to produce three distinct proteins having unique carboxy-terminals. Two variants, MAGI-1a and MAGI-1b, are associated with the membrane and cytosolic fractions and are primarily expressed in the brain. The third isoform, MAGI-1c, encodes for a nuclear localization signal that localizes MAGI-1c to the nucleus, and it is primarily expressed in the liver and kidney. MAGI-2 and MAGI-3 are localized to the plasma membrane, and they contribute to protein scaffolding by associating with the protein phosphatase PTEN.For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Replacement monoclonal antibody for: sc-11526, sc-11527, sc-11528, sc-11529, sc-25664.

IGG-免疫球蛋白G型抗体

HumanMAGI2

human

9863;50791