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Mouse Monoclonal MALT1 Antibody (SPM578) - Azide and BSA Free
品牌： Novus
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对比
咨询分子量：
93 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
纯度：
Protein A or G purified
产品介绍
产品介绍
产品信息
荧光素标记
Unconjugated
宿主
Mouse
免疫原
Human MALT1 recombinant fragment (aa701-808) (Uniprot: Q9UDY8)
简单描述
1.0 mg/ml of antibody purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS WITHOUT BSA & azide. Also available at 200 ug/ml WITH BSA & azide (NBP2-32872).
Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C.
商品描述
1.0 mg/ml of antibody purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS WITHOUT BSA & azide. Also available at 200 ug/ml WITH BSA & azide (NBP2-32872).
Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C.
同种型
IgG1 Kappa
分子量
93 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
克隆号
SPM578
克隆类别
Monoclonal
纯度
Protein A or G purified
浓度
1.0 mg/ml
防腐剂
No Preservative
基因
MALT1
应用
实验应用
WB, IHC, CyTOF-ready
反应种属
Hu
稀释度
CyTOF-ready Immunohistochemistry Immunohistochemistry-Paraffin 0.5-1ug/mlWestern Blot 0.5-1ug/ml
背景
别名
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
背景
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1), also known as MLT1 or paracaspase 1, is a member of the human paracaspase family and an interacting partner of B-cell lymphoma 10 (Bcl-10) (1). In vitro, In vitro, MALT1 synergizes with BCL10 to enhance nuclear factor B activation (2) and to mediate IB kinase (IKK) activation by facilitating the ubiquitinylation of the NF-B essential modulator (NEMO) (3). MALT1 is found in recurrent chromosomal translocations in non-Hodgkin B-cell lymphoma of the mucosa-associated lymphoid tissue (MALT). One common translocation juxtaposes the MALT1 gene to the IgH promoter region, resulting in up-regulation of Bcl-10 and MALT1 (4). Another common translocation creates a fusion between MALT1 and the inhibitor of apoptosis gene API2 (cIAP2/HIAP1) (5).
细胞定位
Cytoplasmic
制备和贮存
保存方式
Store at -20 to -80C. Avoid freeze-thaw cycles.
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