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MCM8, ID (MCM8, C20orf154, DNA replication licensing factor MCM8, Minichromosome maintenance 8)
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产品介绍
产品介绍
产品信息
纯化方式
Affinity Purified
Purified by Protein A affinity chromatography.
抗原名称
MCM8 isoform
免疫原
MCM8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 321-351 amino acids from the Central region of human MCM8.
商品描述
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein contains the central domain that is conserved among the MCM proteins. This protein has been shown to co-immunoprecipitate with MCM4, 6 and 7, which suggests that it may interact with other MCM proteins and play a role in DNA replication. Alternatively spliced transcript variants encoding distinct isoforms have been described.
形式
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
产品类型
Polyclonal
应用
实验应用
ELISA (EL/EIA), Western Blot (WB)
反应种属
Human
背景
别名
Anti -MCM8, ID (MCM8, C20orf154, DNA replication licensing factor MCM8, Minichromosome maintenance 8)
制备和贮存
保存方式
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
数据库链接
NCBI
84515
UniProt ID
Q9UJA3
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