MED26, ID (MED26, ARC70, CRSP7, Mediator of RNA polymerase II transcription subunit 26, Activator-recruited cofactor 70kD component, Cofactor required

Affinity Purified Purified by Protein A affinity chromatography.

mediator of RNA polymerase II transcription subunit 26

MED26 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 190-220 amino acids from the Central region of human MED26.

The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Polyclonal

ELISA (EL/EIA), Western Blot (WB)

Human

Anti -MED26, ID (MED26, ARC70, CRSP7, Mediator of RNA polymerase II transcription subunit 26, Activator-recruited cofactor 70kD component, Cofactor required for Sp1 transcriptional activation subunit 7, Mediator complex subunit 26, Transcriptional coactivator C

9441

O95402 [Other Products]