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MEF-2D (H-11)

产品介绍
产品信息
宿主
mouse

简单描述
抗-MEF-2D 抗体 H-11 是小鼠单克隆 IgG3 κ,MEF-2D抗体, 在8篇文献中引用,规格为200 µg/mlraised against a peptide mapping within an internal region of MEF-2D of human origin推荐用于 mouse, rat 和 human 来源的MEF-2D WB, IP, IF, IHC(P) 和 ELISA检测可用于ChIP的TransCruz试剂(sc-271153 X, 200 µg/0.1 ml)关于如何获取MEF-2D (H-11): sc-271153的免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。m-IgG3 BP-HRP 是MEF-2D Antibody (H-11) for WB and IHC(P)首选应用二抗. 这些试剂现在以套装形式提供MEF-2D Antibody (H-11) (见下方订购信息).
查看产品引用文献(7) MEF-2D Antibody (H-11) is a high quality monoclonal MEF-2D antibody (also designated MEF2D antibody, or myocyte enhancer factor 2D antibody) suitable for the detection of the MEF-2D protein of mouse, rat and human origin. MEF-2D Antibody (H-11) is available as the non-conjugated anti-MEF-2D antibody. The myocyte enhancer factor-2 (MEF-2) family of transcription factors associate with co-repessors or co-activators to regulate development and function of T cells, neuronal cells, and muscle cells. Four family members arise from alternatively spliced transcripts, termed MEF-2A, -2B, -2C, and -2D. These members bind as homo- and heterodimers to the MEF-2 site in the promoter region of affected genes. Differential regulation in the expression of the four transcripts implies functional distinction for each duing embryogenesis and development. The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including MyoD, myogenin, Myf-5, and MRF4, are one class of identified factors. A second family of DNA binding regulatory proteins is the myocyte-specific enhancer factor-2 (MEF-2) family. Each of these proteins binds to the MEF-2 target DNA sequence present in the regulatory regions of many muscle-specific genes.For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

克隆类别
Replacement monoclonal antibody for: sc-13921, sc-13922, sc-366368.

组成成分
IGG-免疫球蛋白G型抗体
