Met-Enkephalinamide (trifluoroacetate salt)

Met-Enkephalinamide is a peptide opioid receptor agonist and derivative of Met-enkephalin (Item No. 23284).1,2 It binds to opioid receptors in rat cerebellum homogenates (IC50 = 0.2 µM) and reduces the twitch height in electrically stimulated isolated guinea pig ileum and isolated mouse vas deferens. Met-Enkephalinamide (300 µg/animal) induces analgesia in the hot plate and tail-flick tests in rats, effects that can be reversed by administration of the opioid receptor antagonist naloxone.3WARNING This product is not for human or veterinary use.

A peptide opioid receptor agonist

572.7

≥98%

Biochemicals/Peptides/Receptor Pharmacology/Agonists

Formal_Name:L-tyrosylglycylglycyl-L-phenylalanyl-L-methioninamide, trifluoroacetate salt;Synonyms:[Met5]-Enkephalin amide Methionine-Enkephalin amide H-Tyr-Gly-Gly-Phe-Met-NH2 H-YGGFM-NH2

O=C(N[C@H](C(N)=O)CCSC)[C@@H](NC(CNC(CNC([C@@H](N)CC(C=C1)=CC=C1O)=O)=O)=O)CC2=CC=CC=C2.OC(C(F)(F)F)

C27H36N6O6S • XCF3COOH

≥ 4 years

DMF: 2 mg/ml DMSO: 10 mg/ml Ethanol: 3 mg/ml PBS (pH 7.2): 2 mg/ml