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产品介绍
产品介绍
产品信息
抗原名称
ATAD5
商品描述
ML367 is a potent inhibitor of ATPase family AAA domain-containing protein 5 ATAD5 stabilization, blocks DNA repair pathways, suppresses general DNA damage responses including RPA32-phosphorylation and CHK1-phosphorylation in response to UV irradiation.
分子量
334.32
纯度
98%
可溶性
DMSO : ≥ 125 mg/mL (373.89 mM)
In vitro(体外研究)
ML367 (0-40 μM, 16 hours) inhibits FLAG-ATAD5 stabilization in HEK293T cells in the presence or absence of 20 μM 5-FUrd.Western Blot AnalysisCell Line:HEK293T cellsConcentration:0-40 μM in the presence or absence of 20 μM 5-FurdIncubation Time:16 hoursResult:Inhibited the increased ATAD5 protein levels induced by 5-Furd.
背景
分子式
C19H12F2N4
CAS号
381168-77-0
制备和贮存
保存方式
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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