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BD Pharmingen™ PerCP-Cy™5.5 Mouse Anti-Human CD10

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BD Pharmingen™ PerCP-Cy™5.5 Mouse Anti-Human CD10

品牌： BD Pharmingen

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反应种属：

Human (QC Testing), Rhesus,Cynomolgus,Baboon (Tested in Development)

来源宿主：

Mouse BALB/c IgG1, κ

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产品介绍

产品信息

耦联标记

PerCP-Cy5.5

抗原名称

CD10

宿主

Mouse BALB/c IgG1, κ

免疫原

Acute CALLA Leukemia Blast Cells

简单描述

The HI10a monoclonal antibody specifically binds to CD10 which is also known as Neutral endopeptidase (NEP), Enkephalinase, Atriopeptidase, and Neprilysin. CD10 is encoded by MME (membrane metallo-endopeptidase). CD10 is a 100 kDa type II transmembrane glycoprotein that has neutral endopeptidase activity and is otherwise known as the Common Acute Lymphoblastic Leukemia Antigen (CALLA). CD10 is expressed on a wide variety of normal and neoplastic cell types. Normal cells expressing CD10 include granulocytes, bone marrow stromal cells, a subset of B-cell progenitors, germinal center B cells and fibroblasts. This cell surface metalloendopeptidase inactivates a number of signaling molecules and serves as a major regulator in the nervous, immune and other systems.

商品描述

HI10a The HI10a monoclonal antibody specifically binds to CD10 which is also known as Neutral endopeptidase (NEP), Enkephalinase, Atriopeptidase, and Neprilysin. CD10 is encoded by MME (membrane metallo-endopeptidase). CD10 is a 100 kDa type II transmembrane glycoprotein that has neutral endopeptidase activity and is otherwise known as the Common Acute Lymphoblastic Leukemia Antigen (CALLA). CD10 is expressed on a wide variety of normal and neoplastic cell types. Normal cells expressing CD10 include granulocytes, bone marrow stromal cells, a subset of B-cell progenitors, germinal center B cells and fibroblasts. This cell surface metalloendopeptidase inactivates a number of signaling molecules and serves as a major regulator in the nervous, immune and other systems.

同种型

Mouse BALB/c IgG1, κ

克隆号

克隆 HI10a (RUO)

产品详情

PerCP-Cy5.5

PerCP-Cy5.5 dye is part of the BD blue family of dyes. This tandem fluorochrome is comprised of a fluorescent protein complex (PerCP) with an excitation maximum (Ex Max) of 482 nm and an acceptor dye with an emission maximum (Em Max) at 676 nm. PerCP-Cy5 is designed to be excited by the blue laser (488-nm) and detected using an optical filter centered near 680 nm (e.g., a 695/40 nm bandpass filter). The donor dye can be partially excited by the Violet (405-nm) laser resulting in cross-laser excitation and fluorescence spillover. Please ensure that your instrument’s configurations (lasers and optical filters) are appropriate for this dye.

格式:PerCP-Cy5.5

激发源:Blue 488 nm

最多激发源:482 nm

最多发射源:676 nm

应用

实验应用

Flow cytometry (Routinely Tested)

推荐用量

5 µl

反应种属

Human (QC Testing), Rhesus,Cynomolgus,Baboon (Tested in Development)

目标/特异性

CD10

背景

别名

MME; CALLA; EPN; NEP; neprilysin; SFE; atriopeptidase; enkephalinase

制备和贮存

存储溶液

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

保存方式

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

文献

研发参考(3) 1. Barclay NA, Brown MH, Birkeland ML, et al, ed. The Leukocyte Antigen FactsBook. San Diego, CA: Academic Press; 1997. 2. Knapp W. W. Knapp .. et al., ed. Leucocyte typing IV : white cell differentiation antigens. Oxford New York: Oxford University Press; 1989:1-1182. 3. Letarte M, Vera S, Tran R, et al. Common acute lymphocytic leukemia antigen is identical to neutral endopeptidase. J Exp Med. 1988; 168(4):1247-1253. (Biology).

参考图片

Flow cytometric analysis of CD10 expression on human REH cells. Cells from the human REH cell line were stained with PerCP-Cy™5.5 Mouse Anti-Human CD10 antibody (Cat. No. 563508, solid line histogram) or PerCP-Cy™5.5 mIgG1, κ Isotype Control (Cat. No. 550795; dashed line histogram). Flow cytometric fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable cells. Flow cytometric analysis was performed using a BD™ LSR II Flow Cytometry System.

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货号：

563508

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供应商现货

100Tst

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当前规格1件起购

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