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MPS1-IN2
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产品介绍
产品介绍
产品信息
抗原名称
Mps1
商品描述
Mps1-IN-2 is a potent Mps1 kianse inhibitor with IC50 value of 145 nM.
分子量
480.6
纯度
>98%
可溶性
DMSO: 14.3 mg/mL
外观
Powder
In vitro(体外研究)
Mps1-IN-2 is a potent, selective and ATP-competitive Mps1 kinase inhibitor, with an IC50 and a Kd of 145 nM and 12 nM. Mps1-IN-2 also shows high affinity for PLK1 and GAK with Kds of 61 and 140 nM, respectively, but shows little or no inhibition on other 352 member kinases. Mps1-IN-2 can induces bypass of a checkpoint-mediated mitotic arrest in U2OS cells.
背景
别名
MPS1-IN2
分子式
C26H36N6O3
CAS号
1228817-38-6
制备和贮存
保存方式
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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