MRT 68601 hydrochlor (10 mg)

121513855

Potent TBK inhibitor

487.04

N-[3-[[5-Cyclopropyl-2-[[4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]amino]propyl]cyclobutanecarboxamide hydrochloride

Potent TBK1 (TANK-binding kinase-1) inhibitor (IC₅₀ = 6 nM). Inhibits the formation of autophagosomes in lung cancer cells.

≥98% (HPLC)

Soluble to 100 mM in water and to 100 mM in DMSO

O=C(C1CCC1)NCCCNC2=C(C3CC3)C=NC(NC4=CC=C(N5CCOCC5)C=C4)=N2.Cl

C₂₅H₃₄N₆O₂.HCl

1962928-25-1