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品牌： BD Pharmingen
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对比
咨询反应种属：
Mouse (QC Testing)
来源宿主：
Rat LOU, also known as Louvain, LOU/C, LOU/M IgG2b, κ
产品介绍
产品信息
荧光素标记
抗原名称
CD45
宿主
Rat LOU, also known as Louvain, LOU/C, LOU/M IgG2b, κ
商品描述
The 30-F11 clone has been reported to react with all isoforms and both alloantigens of CD45, which is found on hematopoietic stem cells and all cells of hematopoietic origin, except erythrocytes. CD45 is a transmembrane glycoprotein which is expressed at high levels on the cell surface, and its presence distinguishes leukocytes from non-hematopoietic cells. CD45 is a member of the Protein Tyrosine Phosphatase (PTP) family, where the intracellular carboxy-terminal region contains two PTP catalytic domains, and the extracellular region is highly variable due to alternative splicing of exons 4, 5, and 6 (designated as A, B, and C, respectively). CD45 isoforms play complex roles in T-cell and B-cell antigen receptor signal transduction and the CD45 isoforms detected in the mouse are cell type-, maturation-, and activation state-specific.
应用
反应种属
Mouse (QC Testing)
背景
别名
Ptprc; LCA; Leukocyte common antigen; T200; Ly-5; Lyt-4
制备和贮存
保存方式
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
数据库链接
Entrez-Gene ID
19264
参考图片
Flow cytometric analysis of CD45 on mouse splenocytes. BALB/c mice splenocytes were stained with the Alexa Fluor® 700 Rat Anti-Mouse CD45 (Cat. No. 560510; shaded histogram) antibody or an Alexa Fluor® 700 Rat IgG2b, κ isotype control (Cat. No.557964; unshaded histogram). The fluorescence histograms were derived from gated events with the forward and side light-scattering characteristics of viable splenocytes. Flow cytometry was performed on a BD LSR II™.
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