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MTAP (42-T)

产品介绍
产品介绍
产品信息
宿主
mouse

简单描述
抗-MTAP 抗体 42-T 是小鼠单克隆 IgG1 κ,MTAP抗体, 在8篇文献中引用,规格为100 µg/ml免疫human物种的重组MTAP推荐用于 mouse, rat 和 human 来源的MTAP WB, IP, IF 和 ELISA检测关于如何获取MTAP (42-T): sc-100782的免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。m-IgG Fc BP-HRP and m-IgG1 BP-HRP 是 MTAP Antibody (42-T) for WB首选应用二抗。这些试剂现在以套装形式提供MTAP Antibody (42-T) (见下方订购信息).
查看产品引用文献(8) MTAP Antibody (42-T) is a high quality monoclonal MTAP antibody (also designated MTAP antibody) suitable for the detection of the MTAP protein of mouse, rat and human origin. MTAP Antibody (42-T) is available as the non-conjugated anti-MTAP antibody. 5′-Deoxy-5′-methylthioadenosine phosphorylase (MTAP, MSAP) catalyzes the reversible phosphorolysis of methylthioadenosine, which is important in polyamine metabolism and for the salvage of adenine and methionine. The gene encoding MTAP maps to human chromosome 9p21 and is linked to the tumor suppressor gene, p16INK4A (2,3). Deficient levels of MTAP can occur in cancers primarily through codeletion of the MTAP gene and the p16INK4A gene (4-6). Cells expressing MTAP and possessing adenine salvage pathway activity may be less susceptible to malignancy due to growth-inhibitory actions of agents (e.g. antifolates), whose mechanism of action, in part, involves thisFor Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

克隆类别
Replacement monoclonal antibody for: sc-17015, sc-17017, sc-292380.

组成成分
甲硫腺苷磷酸化酶抗体
