mTOR (30)

鼠

抗-mTOR抗体(30)是小鼠单克隆IgG1 λ mTOR抗体, 在49篇文献中引用，规格为200 µg/ml免疫rat物种的的氨基酸185-290推荐用于 mouse, rat 和 human 来源的mTOR WB, IP 和 IF检测还可偶联琼脂糖 (sc-517464 AC), 500 µg/ml, 25% agarose, 用于IP; 偶联HRP (sc-517464 HRP), 200 µg/ml, 用于WB, IHC(P) 和ELISA关于如何获取mTOR (30): sc-517464的免费10 µg小样，联系我们技术服务部门 (或者您当地的代理商)了解详情。m-IgG Fc BP-HRP and m-IgG1 BP-HRP 是 mTOR Antibody (30) for WB首选应用二抗。这些试剂现在以套装形式提供mTOR Antibody (30) (见下方订购信息). 查看产品引用文献(49) mTOR Antibody (30) is a high quality monoclonal mTOR antibody (also designated FRAP1 antibody, FRAP2 antibody or mechanistic target of rapamycin kinase antibody) suitable for the detection of the mTOR protein of mouse, rat and human origin. mTOR Antibody (30) is available as both the non-conjugated anti-mTOR antibody form, as well as multiple conjugated forms of anti-mTOR antibody, including agarose, HRP. The PIK-related kinases include Atm, DNA-PKCS and mTOR. The Atm gene is mutated in the autosomal recessive disorder ataxia telangiectasia (AT) that is characterized by cerebellar degeneration and the appearance of dilated blood vessels in the conjunctivae of the eyes. AT cells are hypersensitive to ionizing radiation, impaired in mediating the inhibition of DNA synthesis and they display delays in p53 induction. DNA-PK is a heterotrimeric DNA binding enzyme that is composed of a large subunit, DNA-PKCS, and two smaller subunits collectively known as Ku. The loss of DNA-PK leads to defects in DSB repair and V(D)J recombination. mTOR, also known as FRAP, can autophosphorylate on serine and bind to rapamycin/FKBP. mTOR is also an upstream regulator of S6 kinase and has been implicated in the regulation of p27 and p21 expression. mTOR autophosphorylates at Ser2481 under translationally repressive conditions. Phosphorylation of mTOR at Ser2448 is mediated by p70S6 kinase.For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

雷帕霉素激酶抗体、磷酸盐缓冲液

MouseMtor

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