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MUC5B (Mucin 5 Subtype B, MUC5-B, MUC9, MG1, Oligomeric Mucus/Gel-Forming, Mucin 5,Subtype B, Tracheobronchial, Cervical mucin, High molecular weight

产品介绍
产品介绍
产品信息
抗原来源
Rat

宿主
Rabbit

免疫原
Recombinant protein corresponding to Ala898-Ile1002 of rat MUC5B, expressed in E. coli.

产品用途
Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry. Other applications not tested.

简单描述
Mucins are high molecular mass, highly glycosylated macromolecules that are the major components of mucus secretions. MUC5B is a salivary mucin that is thought to contribute to the lubricating and viscoelastic properties of whole saliva. It is composed of 14.9% protein, 78.1% carbohydrate, and 7% sulfate. Desseyn et al. isolated MUC5B genomic sequence. They found that the central exon encodes a predicted 3,570aa peptide containing 19 subdomains that can be grouped into 4 larger composite units referred to as 'superrepeats'. Since MUC5B and the related proteins MUC2 and MUC5AC are clustered within chromosome 11p15.5, suggesting that they are members of a multigene family. Desseyn et al. reported that the region 3-prime of the large central exon of MUC5B is composed of 18 exons and spans about 10.7 kb.

同种型
IgG

克隆类别
Polyclonal

纯度
Purified by immunoaffinity chromatography.

形式
Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.

应用
实验应用
E IC IHC WB

推荐用量
Western Blot: 1:50-400 Immunocytochemistry: 1:50-500 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100 ELISA: 1:100-1:5000 Optimal dilutions to be determined by the researcher.

反应种属
Rabbit

交叉反应性
Rt

目标/特异性
Recognizes rat MUC5B.

稀释度
Western Blot: 1:50-400 Immunocytochemistry: 1:50-500 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100 ELISA: 1:100-1:5000 Optimal dilutions to be determined by the researcher.
制备和贮存
保存方式
Storage_Temp:-20°C
Storage_and_Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
数据库链接
UniProt ID
Q9HC84

SwissProt
Q9HC84

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