NAP-2 (5C7)

mouse

NAP-2 抗体 5C7 是小鼠单克隆 IgG1，提供 100 µg/ml 免疫human来源的NAP-2全长 推荐用于 human 来源的NAP-2 WB, IP 和 ELISA检测 目前，我们还没有完成NAP-2 抗体 (5C7)的首选二抗检测试剂的鉴定。这项工作正在进行中。 Members of the a-chemokine subfamily of inducible, secreted, pro-inflammatory cytokines contain a similar motif, in which the first two cysteine residues are separated by a single residue (Cys-X-Cys), and are also chemotactic for neutrophils. The platelet basic protein (PBP), a member of the a-chemokine family, resides in the a-granules of platelets and is released upon their activation. Proteolytic cleavage of the amino terminus of PBP leads to the generation of several peptides, which include mature PBP, connective tissue-activating peptide III (CTAP III, also designated low affinity platelet factor IV (LA-PF4)), b-thromboglobulin (b-TG), and neutrophil-activating peptide 2 (NAP-2). PBP and its N-truncated derivatives mediate inflammation and wound healing. Specifically, NAP-2 activates chemotaxis and degranulation in neutrophils during inflammation. The gene encoding human PBP maps to chromosome 4q13.3.For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

IGG-免疫球蛋白G型抗体

HumanPPBP

WB, IP, ELISA

5473