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Native mouse NGF 2.5S protein (>95%)

产品介绍
产品介绍
产品信息
纯化方式
>95% (HPLC)

商品描述
Native mouse NGF 2.5S protein (>95%) (#N-100) is a highly pure, natural, and biologically active protein.

分子量
26 kDa

生物活性
NGF is purified in three forms: the 7S, 2.5S and β. The 2.5S form is 9 amino acids shorter than the β form because of proteolysis that occurs during the purification process1. NGF has been shown to regulate neuronal survival, development, function and plasticity2. The biological effects of NGF are mediated by two receptors: TrkA, which is specific for NGF, and p75NTR, which binds all the neurotrophins3.

可溶性
Sterile water, DMEM at a concentration of at least 10 μg/ml. Centrifuge all product preparations before use (10000 x g 5 min). Repeated freezing/thawing might result in loss of activity.

浓度
EC50 = 0.7 nM.

形式
Lyophilized

组成成分
SPF级天然小鼠神经生长因子2.5S蛋白(>95%)

背景
别名
Nerve Growth Factor 2.5S

制备和贮存
存储溶液
Up to one week at 4°C or four-six weeks at -70°C.

保存方式
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
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