NDRG1 (Protein NDRG1, Differentiation-related Gene 1 Protein, DRG-1, N-myc Downstream-regulated Gene 1 Protein, Nickel-specific Induction Protein Cap4

Affinity Purified Purified by immunoaffinity chromatography.

NDRG1

Synthetic peptide corresponding to GNSAGPKSMEVSC, from human NDRG1, at C-terminal (NP_006087.2, NP_001128714.1).

NDRG1 is a member of the emerging NDRG family involved in stress responses, hormone responses, cell growth, and differentiation. The NDRG1 gene is mapped to human chromosome 8q24.2 and encodes a cytosolic protein containing three unique tandem repeats of 10 hydrophilic aa near the C-terminus. Expression of NDRG1 is markedly upregulated in various cells under such conditions as cell differentiation, hypoxia and exposure to heavy metals. However, its expression is repressed by the Myc family transcription factors and after cellular transformation. Mutations in the NDRG1 gene are linked to the hereditary motor and sensory neuropathy. The protein is ubiquitously expressed in human and rat heart, brain, kidney, placenta, lung, liver, skeletal muscle, and pancreas.

Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.

Polyclonal

ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)

Canine, Human, Mouse, Rat

Anti -NDRG1 (Protein NDRG1, Differentiation-related Gene 1 Protein, DRG-1, N-myc Downstream-regulated Gene 1 Protein, Nickel-specific Induction Protein Cap43, Reducing Agents and Tunicamycin-responsive Protein, RTP, Rit42, CAP43, DRG1)

10397

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