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NEDD4 (E3 Ubiquitin-Protein Ligase NEDD4)
NEDD4 (E3 Ubiquitin-Protein Ligase NEDD4)
品牌： Usbiological
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对比
咨询纯度：
Purified by immunoaffinity chromatography.
反应种属：
Rabbit
产品介绍
产品介绍
产品信息
抗原来源
Human
宿主
Rabbit
免疫原
Recombinant protein corresponding to human NEDD4 (Position: N960-F1245), expressed in E. coli.
产品用途
Suitable for use in ELISA, Western Blot Other applications not tested.
简单描述
E3 ubiquitin-protein ligase NEDD4, also known as neural precursor cell expressed developmentally down-regulated protein 4 (NEDD4), is an enzyme that in humans is encoded by the NEDD4 gene. This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation. The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and, a C-terminal HECT ubiquitin ligase catalytic domain. It plays critical role in the regulation of a number of membrane receptors, endocytic machinery components and the tumor suppressor PTEN.
同种型
IgG
克隆类别
Polyclonal
纯度
Purified by immunoaffinity chromatography.
形式
Supplied as a lyophilized powder from PBS, 5% BSA, 0.05% sodium azide. Reconstitute with 200ul sterile ddH2O.
应用
实验应用
E WB
推荐用量
ELISA: 0.1-0.5ug/ml Western Blot: 0.1-0.5ug/ml Optimal dilutions to be determined by the researcher.
反应种属
Rabbit
交叉反应性
Hu Mo Rt
目标/特异性
Recognizes human NEDD4. Species Crossreactivity: mouse, rat.
稀释度
ELISA: 0.1-0.5ug/ml Western Blot: 0.1-0.5ug/ml Optimal dilutions to be determined by the researcher.
制备和贮存
保存方式
Storage_Temp:-20°C
Storage_and_Stability:Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
数据库链接
UniProt ID
P46934
SwissProt
P46934
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