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Nefopam hydrochloride
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产品介绍
产品介绍
产品信息
抗原名称
(beta)-catenin
商品描述
Nefopam hydrochloride is an centrally-acting but non-opioid analgesic drug by blocking voltage-gated sodium channel and inhibition of serotonin, dopamine and noradrenaline reuptake.
分子量
289.8
纯度
>98%
可溶性
DMSO ：1 mg/mL (3.45 mM)
Water ：19 mg/mL (65.6 mM)
Water ：19 mg/mL (65.6 mM)
外观
白色结晶性粉末
In vitro(体外研究)
The mechanism of analgesia is not completely understood, it appears that nefopam is a centrally acting, non-opioid analgesic that inhibits reuptake of serotonin, norepinephrine, and dopamine.
In vivo(体内研究)
Using the tail-flick and hot-plate assays, nefopam is tested for analgesic activity following intraperitoneal (i.p.), intracranial (i.c.) and intraspinal (i.s.) injection in mice. Nefopam is one-third as potent as morphine on the hot-plate test, but does not affect the tail-flick. .
背景
别名
盐酸奈福泮；Fenazoxine hydrochloride
分子式
C17H19NO.HCl
CAS号
23327-57-3
制备和贮存
保存方式
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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