
产品介绍
产品信息
宿主
mouse

简单描述
NF-L抗体(NR4)是小鼠单克隆IgG1 κ, 在2篇文献中引用,规格为200 µg/ml免疫porcine物种的NF-Lrecommended for detection of NF-L of mouse, rat and human origin by IF; 也和以下物种反应,包括: porcine; 不会与 other intermediate filament proteins产生交联反应m-IgG Fc BP-HRP and m-IgG1 BP-HRP 是 NF-L Antibody (NR4) for WB and IHC(P)首选应用二抗。这些试剂现在以套装形式提供NF-L Antibody (NR4) (见下方订购信息).
查看产品引用文献(2) Neurofilament-L (NF-L), for neurofilament light polypeptide, a member of the intermediate filament family, is a major component of neuronal cyto-skeletons. Neurofilaments are dynamic structures; they contain phosphorylation sites for a large number of protein kinases, including protein kinase A, protein kinase C, cyclin-dependent kinase 5, extracellular signal regulated kinase, glycogen synthase kinase-3 and stress-activated protein kinase gamma. In addition to their role in the control of axon caliber, neurofilaments may affect other cytoskeletal elements, such as microtubules and Actin filaments. Changes in neurofilament phosphorylation or metabolism are frequently observed in neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS), Parkinson's disease and Alzheimer's disease.For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

组成成分
IGG-免疫球蛋白G型抗体

应用
实验应用
IF

数据库链接
Entrez-Gene ID
4747;18039

声明 :本官网所有报价均为常温或者蓝冰运输价格,如有产品需要干冰运输,需另外加收干冰运输费。