NGFR p75 (NGFR5)

mouse

NGFR p75抗体(NGFR5)是小鼠单克隆IgG1 κ, 在5篇文献中引用，规格为200 µg/mlraised against NGFR p75 from A875 melanoma cells of human origin推荐用于 human 和 feline 来源的NGFR p75 WB, IP, IF, IHC(P) 和 FCM检测; 不会与 mouse or rat NGFR p75产生交联反应看 NGFR p75 (B-1): sc-271708，可查看有标记的 NGFR p75 抗体，包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790m-IgG Fc BP-HRP and m-IgG1 BP-HRP 是 NGFR p75 Antibody (NGFR5) for WB and IHC(P)首选应用二抗。这些试剂现在以套装形式提供NGFR p75 Antibody (NGFR5) (见下方订购信息). 查看产品引用文献(5) The Trk oncogene encodes a membrane-spanning protein tyrosine kinase, gp140Trk, whose expression is restricted in vivo to neurons of the sensory spinal and cranial ganglia of neural crest origin. Nerve growth factor (NGF) stimulates tyrosine phosphorylation of Trk A in neural cell lines and in embryonic dorsal root ganglia. Tyrosine phosphorylation of Trk by NGF is rapid, specific and occurs with picomolar quantities of factor, indicating that the response is mediated by physiological amounts of NGF, suggesting that Trk A participates in the primary signal transduction mechanism of NGF. An additional component of the Trk A receptor complex, NGFR p75, binds to the neurotrophic factors with low affinity but is required for efficient signaling. NGFR p75 accelerates Trk A activation and may recruit downstream effector molecules to the liganded complex.For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

IGG-免疫球蛋白G型抗体

WB, IP, IF, IHC(P), FCM

4804