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NOS1 (Nitric Oxide Synthase, Brain, 1.14.13.39, Constitutive NOS, NC-NOS, N)

产品介绍
产品介绍
产品信息
抗原来源
Human

宿主
Rabbit

免疫原
Synthetic peptide corresponding to aa1402-1434, of a sequence VTLRTYEVTNRLRSESIAFIEESKKDTDEVFSS of human NOS1.

产品用途
Suitable for use in Western Blot. Other applications not tested.

简单描述
Nitric oxide synthase 1 (neuronal), also known as NOS1, is an enzyme that in humans is encoded by the NOS1 gene. The protein encoded by this gene belongs to the family of nitric oxide synthases, which synthesize nitric oxide from L-arginine. Nitric oxide is a reactive free radical, which acts as a biologic mediator in several processes, including neurotransmission, and antimicrobial and antitumoral activities. In the brain and peripheral nervous system, nitric oxide displays many properties of a neurotransmitter, and has been implicated in neurotoxicity associated with stroke and neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis, and penile erection. This protein is ubiquitously expressed, with high level of expression in skeletal muscle. Multiple transcript variants that differ in the 5' UTR have been described for this gene but the full-length nature of these transcripts is not known. Additionally, alternatively spliced transcript variants encoding different isoforms (some testis-specific) have been found for this gene.

同种型
IgG

克隆类别
Polyclonal

纯度
Purified by immunoaffinity chromatography.

形式
Supplied as a lyophilized powder from PBS, 5% BSA, 0.05% sodium azide. Reconstitute with 200ul sterile ddH2O.

应用
实验应用
WB

推荐用量
Western Blot: 0.1-0.5ug/ml Optimal dilutions to be determined by the researcher.

反应种属
Rabbit

交叉反应性
Hu Mo Rt

目标/特异性
Recognizes human NOS1. Species Crossreactivity: mouse, rat.

稀释度
Western Blot: 0.1-0.5ug/ml Optimal dilutions to be determined by the researcher.
制备和贮存
保存方式
Storage_Temp:-20°C
Storage_and_Stability:Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
数据库链接
UniProt ID
P29475

SwissProt
P29475

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