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NOX4 (NADPH Oxidase 4, Kidney Oxidase-1, KOX-1, Kidney Superoxide-Producing NADPH Oxidase, Renal NAD(P)H-Oxidase, RENOX)
NOX4 (NADPH Oxidase 4, Kidney Oxidase-1, KOX-1, Kidney Superoxide-Producing NADPH Oxidase, Renal NAD(P)H-Oxidase, RENOX)
品牌： Usbiological
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对比
咨询纯度：
Purified by immunoaffinity chromatography.
反应种属：
Rabbit
产品介绍
产品介绍
产品信息
抗原来源
Human
宿主
Rabbit
免疫原
Synthetic peptide corresponding to sequence ILNTLLDDWKPYKLRRLYFIWVCRDIQSFRWFADLL of human NOX4.
产品用途
Suitable for use in Western Blot, Immunohistochemistry. Other applications not tested.
简单描述
NADPH oxidase 4 is an enzyme that in humans is encoded by the NOX4 gene, and is a member of the NOX family of NADPH oxidases. This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.
同种型
IgG
克隆类别
Polyclonal
纯度
Purified by immunoaffinity chromatography.
形式
Supplied as a lyophilized powder from PBS, 5% BSA, 0.05% sodium azide. Reconstitute with 200ul sterile ddH2O.
应用
实验应用
IHC WB
推荐用量
Western Blot: 0.1-0.5ug/ml Immunohistochemistry (paraffin): 0.5-1ug/ml Optimal dilutions to be determined by the researcher.
反应种属
Rabbit
交叉反应性
Hu Mo Rt
目标/特异性
Recognizes human NOX4. Species Crossreactivity: mouse, rat.
稀释度
Western Blot: 0.1-0.5ug/ml Immunohistochemistry (paraffin): 0.5-1ug/ml Optimal dilutions to be determined by the researcher.
制备和贮存
保存方式
Storage_Temp:-20°C
Storage_and_Stability:Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
数据库链接
UniProt ID
Q9NPH5
SwissProt
Q9NPH5
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