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NPRL3 (Biotin)
品牌： Usbiological
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对比
咨询纯度：
Purified by Protein G affinity chromatography.
反应种属：
Rabbit
产品介绍
产品介绍
产品信息
荧光素标记
Biotin
抗原来源
Human
宿主
Rabbit
免疫原
Recombinant protein corresponding to aa349-482 from human GATOR complex protein NPRL3.
产品用途
Suitable for use in ELISA. Other applications not tested.
简单描述
As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC-containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling. The GATOR1 complex is negatively regulated by GATOR2 the other GATOR subcomplex in this amino acid-sensing branch of the TORC1 pathway.
同种型
IgG
克隆类别
Polyclonal
纯度
Purified by Protein G affinity chromatography.
形式
Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol. Labeled with Biotin.
应用
实验应用
E
推荐用量
Optimal dilutions to be determined by the researcher.
反应种属
Rabbit
交叉反应性
Hu
目标/特异性
Recognizes human NPRL3.
稀释度
Optimal dilutions to be determined by the researcher.
背景
别名
GATOR complex protein NPRL3 (-14 gene protein) (Alpha-globin regulatory element-containing gene protein) (Nitrogen permease regulator 3-like protein) (Protein CGTHBA), NPRL3, C16orf35 CGTHBA MARE
制备和贮存
保存方式
Storage_Temp:-20°C
Storage_and_Stability:Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
数据库链接
UniProt ID
Q12980
SwissProt
Q12980
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