NR3C1, ID (NR3C1, GRL, Glucocorticoid receptor, Nuclear receptor subfamily 3 group C member 1)

NR3C1, ID (NR3C1, GRL, Glucocorticoid receptor, Nuclear receptor subfamily 3 group C member 1)

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品牌: MyBioSource
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反应种属:
Human, Mouse
实验应用:
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
产品介绍
产品信息
纯化方式
Affinity Purified Purified by Protein A affinity chromatography.
抗原名称
NR3C1
免疫原
NR3C1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 243-272 amino acids from the Central region of human NR3C1.
商品描述
NR3C1 is a receptor for glucocorticoids that can act as both a transcription factor and as a regulator of other transcription factors. This protein can also be found in heteromeric cytoplasmic complexes along with heat shock factors and immunophilins. The protein is typically found in the cytoplasm until it binds a ligand, which induces transport into the nucleus. Mutations in this gene are a cause of glucocorticoid resistance, or cortisol, resistance. Alternate splicing, the use of at least three different promoters, and alternate translation initiation sites result in several transcript variants encoding the same protein or different isoforms, but the full-length nature of some variants has not been determined.
形式
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
产品类型
Polyclonal
应用
实验应用
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
反应种属
Human, Mouse
背景
别名
Anti -NR3C1, ID (NR3C1, GRL, Glucocorticoid receptor, Nuclear receptor subfamily 3 group C member 1)
制备和贮存
保存方式
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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货号:
MBS644677-0.2mL
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询价
0.2mL
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