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产品信息
商品描述
Oleyoxyethyl Phosphorylcholine is used as a potent inhibitor in order to investigate the various biological roles of phospholipase A2 (PLA2). Recent studies include using oleyoxyethyl phosphorylcholine as a PLA2 inhibitor in tobacco hornworm salivary glands which disrupted the hydrolysis of arachidonic acid. Oleyoxyethyl Phosphorylcholine has been shown to inhibit PLA2 ethanol-induced contraction of gastric smooth muscle and also reduced axonal outgrowth from the sciatic nerve stump. This compound is also found to inhibit the myogenic response of isolated renal arcuate arteries. In addition, oleyoxyethyl phosphorylcholine may be used to inhibit sPLA2.
分子量
477.7
纯度
98%
可溶性
DMF : >16 mg/ml
DMSO : >16 mg/ml
Ethanol : >15 mg/ml
DMSO : >16 mg/ml
Ethanol : >15 mg/ml
外观
solution in ethanol
IC50
porcine pancreatic PLA2: IC50 = 6.2 µM (porcine); human recombinant sPLA2: IC50 = 13.7 µM (human)
应用
实验应用
A potent inhibitor of PLA2
背景
分子式
C25H52NO5P
CAS号
84601-19-4
制备和贮存
保存方式
Store at -20° C，2 years.
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