OTX1 (3A5)

mouse

抗-OTX1 抗体 3A5 是小鼠单克隆 IgG2a κ，OTX1抗体, 在2篇文献中引用，规格为100 µg/mlraised against amino acids 10-116 representing partial length OTX1 of human origin推荐用于 mouse, rat 和 human 来源的OTX1 WB, IP, IF 和 ELISA检测关于如何获取OTX1 (3A5): sc-517000的免费10 µg小样，联系我们技术服务部门 (或者您当地的代理商)了解详情。目前，我们还没有完成OTX1 抗体 (3A5)的首选二抗检测试剂的鉴定。这项工作正在进行中。 查看产品引用文献(2) OTX1 Antibody (3A5) is a high quality monoclonal OTX1 antibody (also designated OTX1 antibody) suitable for the detection of the OTX1 protein of mouse, rat and human origin. OTX1 Antibody (3A5) is available as the non-conjugated anti-OTX1 antibody. Transcription factors, OTX1 and OTX2, are two murine homologs of the Drosophila orthodenticle (OTD), show a limited amino acid sequence divergence. OTX1 and OTX2 play an important role during early and later events required for proper brain development in that they are involved in the processes of induction, specification and regionalization of the brain. OTX1 is involved in corticogenesis, sensory organ development and pituitary functions, while OTX2 is necessary earlier in development, for the correct anterior neural plate specification and organization of the primitive streak. OTX2 is also required in the early specification of the neuroectoderm, which is destined to become the fore-midbrain, and both OTX1 and OTX2 co-operate in patterning the developing brain through a dosage-dependent mechanism. A molecular mechanism depending on a precise threshold of OTX proteins is necessary for the correct positioning of the isthmic region and for anterior brain patterning. The genes which encode OTX1 and OTX2 map to human chromosomes 2p13 and 14q21-q22, respectively.For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Replacement monoclonal antibody for: sc-11026, sc-133872, sc-292314.

HumanOTX1

human

5013;18423