P2RY12

Purified recombinant protein fragment corresponding to human P2RY12, expressed in E. coli..

Suitable for use in ELISA, Flow Cytometry and Western Blot . Other applications not tested.

The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity which overlaps in some cases for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8). Alternative splicing results in multiple transcript variants of this gene.

IgG1

1C2A9

Monoclonal

Purified

Suitable for use in ELISA, Flow Cytometry and Western Blot . Other applications not tested.

ELISA: 1:10,000 Flow Cytometry: 1:200-1:400 Western Blot: 1:500-1:2000 Optimal dilutions to be determined by the researcher.

Mouse

Hu

Recognizes human P2RY12.

HORK3; P2Y12; ADPG-R; BDPLT8; SP1999; P2T(AC); P2Y(AC); P2Y(12)R; P2Y(ADP); P2Y(cyc)