

产品介绍
产品信息
宿主
mouse

简单描述
抗-p53抗体(DO-1)是小鼠单克隆IgG2a κ p53抗体, 在5,758篇文献中引用,规格为200 µg/mlN-terminal抗原表位位于human来源的p53的11-25氨基酸残基之间抗-p53 抗体 (DO-1) 推荐用于 WB, IP, IF, IHC(P) 和 FCM,检测mouse, rat 和human 来源的 wild type and mutant p53 under denaturing and non-denaturing conditions抗-p53 抗体 (DO-1) 可偶联 琼脂糖 用于 IP; HRP 用于 WB, IHC(P) 和 ELISA; 还可偶联 藻红蛋白 或者 FITC 用于 IF, IHC(P) 和 FCM还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 和 Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统还可偶联Alexa Fluor® 680 和 Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统还可偶联生物素 用于WB, IHC(P) 和ELISA; 偶联TRITC, PerCP, PerCP-Cy5.5 以及 Alexa Fluor® 405 用于IF, IHC(P) 和 FCM可用于凝胶迁移和ChIP的TransCruz试剂(sc-126 X, 200 µg/0.1 ml)关于如何获取p53 (DO-1): sc-126的免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。m-IgG Fc BP-HRP and m-IgG2a BP-HRP 是 p53 Antibody (DO-1) for WB and IHC(P)首选应用二抗。这些试剂现在以套装形式提供p53 Antibody (DO-1) (见下方订购信息).
查看产品引用文献(5666) p53 Antibody (DO-1) is a high quality monoclonal p53 antibody (also designated tumor suppressor protein p53 antibody or TP53 antibody) suitable for the detection of the p53 protein of mouse, rat and human origin. p53 Antibody (DO-1) is available as both the non-conjugated anti-p53 antibody form, as well as multiple conjugated forms of anti-p53 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The 53 protein is a DNA-binding, oligomerization domain- and transcription activation domain-containing tumor suppressor. The p53 protein upregulates growth arrest and apoptosis-related genes in response to stress signals, thereby influencing programmed cell death, cell differentiation, and cell cycle control mechanisms. The p53 Antibody can stain both the nucleus and cytoplasm, as the p53 protein localizes to the nucleus, yet can be chaperoned to the cytoplasm by the negative regulator, MDM2. MDM2 is an E3 ubiquitin

克隆类别
Replacement monoclonal antibody for: sc-1314, sc-6243, sc-1311, sc-6243-G, sc-1311-R.

组成成分
肿瘤抑制蛋白p53抗体,磷酸盐缓冲液
