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PathPlus™ Rhodopsin / RHO Antibody (Extracellular Domain) LS-A1052
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产品介绍
产品介绍
产品信息
荧光素标记
纯化方式
Immunoaffinity purified
抗原名称
Human Rhodopsin / RHO
宿主
Rabbit
免疫原
Synthetic 19 amino acid peptide from 2nd extracellular domain of human RHO / Rhodopsin. Percent identity with other species by BLAST analysis: Human, Monkey, Mouse, Rat, Rabbit, Pig, Cat, Elephant, Zebra finch (100%).
商品描述
Retinitis pigmentosa is an inherited progressive disease which is a major cause of blindness in western communities. It can be inherited as an autosomal dominant, autosomal recessive, or X-linked recessive disorder. In the autosomal dominant form,which comprises about 25% of total cases, approximately 30% of families have mutations in the gene encoding the rod photoreceptor-specific protein rhodopsin. This is the transmembrane protein which, when photoexcited, initiates the visual transduction cascade. Defects in this gene are also one of the causes of congenital stationary night blindness.
References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
产品类型
Polyclonal
应用
实验应用
IHC, IHC-P
推荐用量
IHC
IHC - Paraffin (1 - 3 µg/ml)
反应种属
Human, Monkey, Mouse, Rat, Pig, Rabbit
目标/特异性
Human RHO / Rhodopsin. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
背景
别名
RHO | CSNBAD1 | OPN2 | Rhodopsin | RP4 | Opsin 2, rod pigment | Opsin-2
制备和贮存
保存方式
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
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