BD Pharmingen™ FITC Mouse Anti-Human PCNA Set

PCNA

The P roliferating C ell N uclear A ntigen (PCNA) was initially identified as a nuclear antigen in proliferating cells and was subsequently described as a subunit for DNA polymerase δ.  PCNA protein levels peak during the S-phase of the cell cycle, at which time it forms a complex with the p21 inhibitor. PCNA is almost undetectable in other phases of the cycle. Because of its unique expression, PCNA has been extensively used in studies associating the prognosis of tumor progression and neoplastic proliferation.  Human PCNA has been reported to be 262 amino acids with an apparent molecular weight of 36 kDa.

克隆 PC10 (RUO)

Intracellular staining (flow cytometry) (Routinely Tested)

Human (QC Testing)

PCNA