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PD1
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产品介绍
产品介绍
产品信息
免疫原
Purified recombinant protein fragment corresponding to aa192-288 from human PD1, expressed in E. coli.
产品用途
Suitable for use in ELISA, Flow Cytometry and Western Blot. Other applications not tested.
简单描述
This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.
同种型
IgG1
克隆号
8G5B12
克隆类别
Monoclonal
纯度
Purified
应用
实验应用
Suitable for use in ELISA, Flow Cytometry and Western Blot. Other applications not tested.
推荐用量
ELISA: 1:10,000 Flow Cytometry: 1:200-1:400 Western Blot: 1:500-1:2000 Optimal dilutions to be determined by the researcher.
反应种属
Mouse
交叉反应性
Hu
目标/特异性
Recognizes human PD1.
背景
别名
PDCD1; PD-1; CD279; SLEB2; hPD-1; hPD-l; hSLE1
制备和贮存
保存方式
-20°C
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