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产品介绍
产品介绍
产品信息
抗原来源
Human
宿主
Mouse
免疫原
Purified recombinant protein fragment corresponding to aa192-288 from human PD1, expressed in E. coli.
产品用途
Suitable for use in ELISA, Flow Cytometry and Western Blot. Other applications not tested.
简单描述
This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.
同种型
IgG1
克隆号
8G5B12
克隆类别
Monoclonal
纯度
Purified
形式
Supplied as a liquid in PBS, 0.05% sodium azide.
应用
实验应用
E FC WB
推荐用量
ELISA: 1:10,000 Flow Cytometry: 1:200-1:400 Western Blot: 1:500-1:2000 Optimal dilutions to be determined by the researcher.
反应种属
Mouse
交叉反应性
Hu
目标/特异性
Recognizes human PD1.
稀释度
ELISA: 1:10,000 Flow Cytometry: 1:200-1:400 Western Blot: 1:500-1:2000 Optimal dilutions to be determined by the researcher.
背景
别名
PDCD1; PD-1; CD279; SLEB2; hPD-1; hPD-l; hSLE1
制备和贮存
保存方式
Storage_Temp:-20°C
Storage_and_Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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