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PDX1, phosphorylated (T11) (PDX1, IPF1, Pancreas/duodenum homeobox protein 1, Glucose-sensitive factor, Insulin promoter factor 1, Insulin upstream fa


品牌: MyBioSource








反应种属:
Human
实验应用:
ELISA (EL/EIA), Gel Shift Assay (GS/EMSA)
产品介绍
产品介绍
产品信息
纯化方式
Affinity Purified
Purified by Protein A affinity chromatography.

抗原名称
pyruvate dehydrogenase protein x component, Pdx1 (predicted)

免疫原
Phospho-PDX1-T11 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide between 1~30 amino acids surrounding T11 of human PDX1.

商品描述
PDX1 is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this protein are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).

形式
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

产品类型
Polyclonal

应用
实验应用
ELISA (EL/EIA), Gel Shift Assay (GS/EMSA)

反应种属
Human

背景
别名
Anti -PDX1, phosphorylated (T11) (PDX1, IPF1, Pancreas/duodenum homeobox protein 1, Glucose-sensitive factor, Insulin promoter factor 1, Insulin upstream factor 1, Islet/duodenum homeobox-1, Somatostatin-transactivating factor 1)

制备和贮存
保存方式
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
数据库链接
NCBI
2539081

UniProt ID
O94709
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