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产品介绍
产品介绍
产品信息
荧光素标记
纯化方式
Protein A
抗原名称
PD-1
宿主
Human
同种型
IgG4,k
浓度
5 mg/ml
性状
Liquid
缓冲体系
PBS pH7.4, containing no preservative.
Endotoxin level is ≤ 1 EU/mg
产品类型
Recombinant mAb
应用
实验应用
Blocking of PD-1/PD-L1 signaling Functional assays
反应种属
Hu
背景
背景
Pembrolizumab is a humanized monoclonal IgG4 kappa antibody directed against human cell surface PD-1 (programmed death receptor-1) on lymphocytes. The PD-1 receptor provides an important “immune checkpoint,” which helps prevent the immune system from attacking itself.
制备和贮存
保存方式
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
文献
文献
参考图片
Pembrolizumab (anti-PD-1), dilutions start from 1 μg/ml) can bind to Immobilized recombinant Human PD-1 his tag (UA010004 form UA.BIO) at 0.5 μg/ml (50 μl/well) as coating antigen.
EC50=13.74 ng/ml
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