PepTivator^® SARS-CoV-2 MHC-I Select, research grade

Stimulate CD8⁺ T cells reactive to SARS-CoV-2 using PepTivator Peptide Pools. MHC-I specific PepTivators are pools of lyophilized peptides, consisting of MHC class I-restricted peptides of 8–12 aa length. PepTivator SARS-CoV-2 MHC-I Select covers selected epitopes of the whole proteome of SARS-CoV-2 (GenBank MN908947.3) without the surface or spike glycoprotein (“S”). In contrast, PepTivator SARS-CoV-2 MHC-I Select Prot_S covers selected epitopes of the SARS-CoV-2 surface or spike glycoprotein (“S”) (GenBank MN908947.3, Protein QHD43416.1).

In vitro stimulation of antigen-specific T cells with PepTivator Peptide Pools causes the secretion of effector cytokines and the up-regulation of activation markers, which then allow the detection and isolation of antigen-specific T cells.