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PI3K p85 (alpha)
品牌： Usbiological
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对比
咨询纯度：
Purified by Protein A/G affinity chromatography.
反应种属：
Mouse
产品介绍
产品信息
免疫原
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
产品用途
Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunofluorescence, Immunoprecipitation. Other applications not tested.
简单描述
Phosphatidylinositol 3-kinase (PI3K) plays an important role in the metabolic actions of insulin and is required for adipogenesis. The PI3K pathway has also been identified as an important player in cancer development and progression. The Class IA PI3K heterodimer, which is composed of a P110 catalytic subunit and a P85 regulatory subunit, is activated upon association of the P85 subunit with upstream adaptor proteins or receptor tyrosine kinases. Mutations in PIK3R1 are implicated in cases of breast cancer and associated to SHORT syndrome.
同种型
IgG1
克隆号
19D363
克隆类别
Monoclonal
纯度
Purified by Protein A/G affinity chromatography.
应用
实验应用
Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunofluorescence, Immunoprecipitation. Other applications not tested.
推荐用量
Western Blot: 1:1000-1:10,000 Immunoprecipitation: 1:200-1:2000 Immunohistochemistry: 1:20-1:200 Immunofluorescence: 1:50-1:500 Optimal dilutions to be determined by the researcher.
反应种属
Mouse
交叉反应性
Hu Mo
目标/特异性
Recognizes PI3K p85(alpha). Species Crossreactivity: human, mouse
背景
别名
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
制备和贮存
保存方式
-20°C
数据库链接
SwissProt
P27986
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