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产品介绍
产品介绍
产品信息
荧光素标记
Unlabeled

宿主
Mouse

商品描述
Purified Mouse Monoclonal Antibody (Mab)

同种型
IgG1

分子量
Predicted molecular weight: 63 kDa

克隆号
38CT20.8.5

克隆类别
Monoclonal Antibody

应用
实验应用
WB~~1:2000 IHC-P~~1:100~500 IF~~1:25

反应种属
Human, Mouse

目标/特异性
Recombinant PINK1 protein was used to produced this monoclonal antibody.

背景
别名
PINK1抗体

研究领域
Cardiovascular;Metabolism;Neuroscience;Signal Transduction
翻译后修饰
Unmodified

细胞定位
Mitochondrion outer membrane; Single-pass membrane protein. Mitochondrion inner membrane {ECO:0000250|UniProtKB:Q99MQ3}; Single-pass membrane protein. Cytoplasm, cytosol. Note=Localizes mostly in mitochondrion and the two smaller proteolytic processed fragments localize mainly in cytosol (PubMed:19229105). When mitochondria lose mitochondrial membrane potential following damage, PINK1 import is arrested, which induces its accumulation in the outer mitochondrial membrane, where it acquires kinase activity (PubMed:18957282)

制备和贮存
存储溶液
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.

保存方式
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
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