PPDA (10 mg)

90488770

GluN2C/GluN2D-selective NMDA antagonist

378.38

(2S*,3R*)-1-(Phenanthren-2-carbonyl)piperazine-2,3-dicarboxylic acid

Subtype-selective NMDA receptor antagonist that preferentially binds to NR2C/NR2D-containing receptors (K_i values are 0.096, 0.125, 0.31 and 0.55 μM for NR2C, NR2D, NR2B and NR2A subunits respectively).

≥98% (HPLC)

Soluble to 50 mM in 2eq. NaOH and to 100 mM in DMSO

O=C(C2=CC=C3C(C=CC4=C3C=CC=C4)=C2)N1[C@@H]([C@](O)=O)[C@@H]([C@](O)=O)NCC1.O=C(C6=CC=C7C(C=CC8=C7C=C

C₂₁H₁₈N₂O₅

684283-16-7