Anti-mesothelin antibody (DM73), Rabbit mAb

Purified from cell culture supernatant by affinity chromatography

mesothelin isoform 1 preproprotein

Recombinant human mesothelin (Glu296-Gly580) produced by using human HEK293 cells

This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

DM73

Liquid. 50% Glycerol; PBS, pH7.4; 0.1% BSA; 0.1% Procline 300

Monoclonal

ELISA (EIA), Flow Cytometry (FC/FACS)

Human

MSLN; Mesothelin; MPF

10232

Q13421 [Other Products]