Anti-TIM3 antibody (DM81), Rabbit mAb

Purified from cell culture supernatant by affinity chromatography

Hepatitis A virus cellular receptor 2

Recombinant human TIM3 (Ser22-Gly202) produced by using human HEK293 cells

The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.

DM81

Liquid. 50% Glycerol; PBS, pH7.4; 0.1% BSA; 0.1% Procline 300

Monoclonal

ELISA (EIA), Flow Cytometry (FC/FACS)

Human

HAVCR2; TIM3; TIMD3; FLJ14428; KIM3

84868

Q8TDQ0 [Other Products]