Anti-CD30 antibody (DM105), Rabbit mAb

Purified from cell culture supernatant by affinity chromatography

tumor necrosis factor receptor superfamily member 8 isoform 1

Recombinant human CD30 (Phe19-Lys379) produced by using human HEK293 cells

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

DM105

Lyophilized from sterile PBS, pH7.4. Normally 5%-8% trehalose is added as protectants before lyophilization. 0.1% Procline 300

Monoclonal

ELISA (EIA), Flow Cytometry (FC/FACS)

Human

TNFRSF8; CD30; D1S166E; Ki-1

943

P28908 [Other Products]