Anti-Hsp90 Monoclonal Antibody

HSP90

Hsp90 and the 94 kDa glucose-regulated protein, Grp94, are major molecular chapeones of the cytosol and endoplasmic reticulum. In mammalian cells, there are at least two Hsp90 isoforms, Hsp90 alpha and Hsp90 beta , which are encoded by separate genes. All known members of the Hsp90 family are highly conserved, especially in the N-terminal and C-terminal regions. In the absence of stress, Hsp90 is an essential component of cellular processes such as hormone signaling and cell cycle control. Several regulatory proteins such as steroid receptors, cell cycle kinases and p53 have been identified as substrates of Hsp90.

100ug in PBS, pH 7.4, purified by Protein G affinity chromatography.

Monoclonal

Immunoblot, Immunohistochemistry, Immunoprecipitation

Hsp90