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Glycogen Synthase Kinase 3 beta, phosphorylated (Ser9) (Glycogen Synthase Kinase-3 beta, GSK-3 beta, GSK3B)


品牌: MyBioSource








反应种属:
Hamster, Human, Mouse, Rat
实验应用:
Western Blot (WB), Immunoprecipitation (IP), Flow Cytometry (FC/FACS), Immunofluorescence (IF)
产品介绍
产品介绍
产品信息
纯化方式
Purified
Purified

抗原名称
glycogen synthase kinase 3 beta

免疫原
Synthetic phosphopeptide corresponding to residues surrounding Ser9 of human GSK-3B.

商品描述
Glycogen synthase kinase-3 (GSK-3) was initially identified as an enzyme that regulates glycogen synthesis in response to insulin (1). GSK-3 is a ubiquitously expressed serine/threonine protein kinase that phosphorylates and inactivates glycogen synthase. GSK-3 is a critical downstream element of the PI3 kinase/Akt cell survival pathway whose activity can be inhibited by Akt-mediated phosphorylation at Ser21 of GSK-3a and Ser9 of GSK-3b (2,3). GSK-3 has been implicated in the regulation of cell fate in Dictyostelium and is a component of the Wnt signaling

克隆号
11C1037

形式
Supplied as a liquid in 10mM sodium HEPES, pH 7.5, 150mM sodium chloride, 100ug/ml BSA, less than 0.02% sodium azide, 50% glycerol.

产品类型
Monoclonal

应用
实验应用
Western Blot (WB), Immunoprecipitation (IP), Flow Cytometry (FC/FACS), Immunofluorescence (IF)

反应种属
Hamster, Human, Mouse, Rat

背景
别名
Anti -Glycogen Synthase Kinase 3 beta, phosphorylated (Ser9) (Glycogen Synthase Kinase-3 beta, GSK-3 beta, GSK3B)

制备和贮存
保存方式
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
数据库链接
NCBI
2932

UniProt ID
P49841
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