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TRAF1, NT (TRAF1, EBI6, TNF receptor-associated factor 1, Epstein-Barr virus-induced protein 6)


品牌: MyBioSource








反应种属:
Human, Mouse
实验应用:
ELISA (EL/EIA), Western Blot (WB)
产品介绍
产品介绍
产品信息
纯化方式
Affinity Purified
Purified by Protein A affinity chromatography.

抗原名称
TNF receptor-associated factor 1 isoform a

免疫原
TRAF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 54-83 amino acids from the N-terminal region of human TRAF1.

商品描述
The protein encoded by this gene is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. The expression of this protein can be induced by Epstein-Barr virus (EBV). EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins; this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors. Three transcript variants encoding two different isoforms have been found for this gene.

形式
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

产品类型
Polyclonal

应用
实验应用
ELISA (EL/EIA), Western Blot (WB)

反应种属
Human, Mouse

背景
别名
Anti -TRAF1, NT (TRAF1, EBI6, TNF receptor-associated factor 1, Epstein-Barr virus-induced protein 6)

制备和贮存
保存方式
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
数据库链接
NCBI
7185

UniProt ID
Q13077
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