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FAIM3 (Fas Apoptotic Inhibitory Molecule 3, Regulator of Fas-induced Apoptosis Toso, TOSO)
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产品介绍
产品介绍
产品信息
纯化方式
Affinity Purified
Purified by Protein A affinity chromatography.
抗原名称
fas apoptotic inhibitory molecule 3 isoform c
免疫原
Partial recombinant corresponding to aa124-223 from FAIM3 (AAH06401) with GST tag. MW of the GST tag alone is 26kD.
商品描述
May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation.
克隆号
1E4
形式
Supplied as a liquid in PBS, pH 7.2.
产品类型
Monoclonal
应用
实验应用
ELISA (EL/EIA), Western Blot (WB)
反应种属
Human
背景
别名
Anti -FAIM3 (Fas Apoptotic Inhibitory Molecule 3, Regulator of Fas-induced Apoptosis Toso, TOSO)
制备和贮存
保存方式
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
数据库链接
NCBI
9214
UniProt ID
O60667
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