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CREB1, ID (CREB, Cyclic AMP-Responsive Element-Binding Protein 1)
品牌： MyBioSource
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对比
咨询反应种属：
Human, Mouse, Rat
实验应用：
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
产品介绍
产品介绍
产品信息
纯化方式
Affinity Purified
Purified by immunoaffinity chromatography
抗原名称
cyclic AMP-responsive element-binding protein 1 isoform B
免疫原
Synthetic peptide corresponding to human CREB1/CREB.
商品描述
CREB (cAMP response element binding protein1), a DNA binding protein, is a member of the leucine zipper family of transcription factors. CREB interaction with DNA requires phosphorylation at Ser 119 by activated cAMP protein kinase A. Once phosphorylated CREB binds to an 8 base enhancer know as the cAMP response element (CRE) containing a conserved core sequence TGACG. CREB also interacts with CBP (CREB binding protein) and RNA polymerase II when phosphorylated on Ser 133. Different isoforms of this protein are the result of two transcript variants.
形式
Supplied as a liquid in PBS, (without Mg2+, Ca2+), pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
产品类型
Polyclonal
应用
实验应用
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
反应种属
Human, Mouse, Rat
背景
别名
Anti -CREB1, ID (CREB, Cyclic AMP-Responsive Element-Binding Protein 1)
制备和贮存
保存方式
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
数据库链接
NCBI
1385
UniProt ID
P16220
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