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p27kip1, CT (Cyclin-dependent Kinase Inhibitor 1B, Cyclin-dependent Kinase Inhibitor p27, CDKN1B, KIP1)


品牌: MyBioSource








反应种属:
Human
实验应用:
Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)
产品介绍
产品介绍
产品信息
纯化方式
Affinity Purified
Purified by immunoaffinity chromatography.

抗原名称
p27kip1

免疫原
Synthetic peptide corresponding to human p27 at C-terminal (KLH).

商品描述
CDKN1B binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state.

形式
Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide.

产品类型
Polyclonal

应用
实验应用
Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)

反应种属
Human

背景
别名
Anti -p27kip1, CT (Cyclin-dependent Kinase Inhibitor 1B, Cyclin-dependent Kinase Inhibitor p27, CDKN1B, KIP1)

制备和贮存
保存方式
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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