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ENPP1 (Ectonucleotide Pyrophosphatase/Phosphodiesterase Family Member 1, E-NPP 1, Membrane Component Chromosome 6 Surface Marker 1, Phosphodiesterase
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产品介绍
产品介绍
产品信息
纯化方式
Affinity Purified
Purified by Protein A affinity chromatography.
抗原名称
ectonucleotide pyrophosphatase/phosphodiesterase family member 1
免疫原
Full length human ENPP1, aa1-873 (NP_006199.1).
商品描述
This gene is a member of the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family. The encoded protein is a type II transmembrane glycoprotein comprising two identical disulfide-bonded subunits. This protein has broad specificity and cleaves a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds of nucleotides and nucleotide sugars. This protein may function to hydrolyze nucleoside 5' triphosphates to their corresponding monophosphates and may also hydrolyze diadenosine polyphosphates. Mutations in this gene have been associated with 'idiopathic' infantile arterial calcification, ossification of the posterior longitudinal ligament of the spine (OPLL), and insulin resistance.
形式
Supplied as a liquid in PBS, pH 7.2.
产品类型
Polyclonal
应用
实验应用
Western Blot (WB)
反应种属
Human
背景
别名
Anti -ENPP1 (Ectonucleotide Pyrophosphatase/Phosphodiesterase Family Member 1, E-NPP 1, Membrane Component Chromosome 6 Surface Marker 1, Phosphodiesterase I/Nucleotide Pyrophosphatase 1, Plasma-cell Membrane Glycoprotein PC-1, M6S1, NPPS, PC1, PDNP1)
制备和贮存
保存方式
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
数据库链接
NCBI
5167
UniProt ID
P22413
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