LDB3, ID (LDB3, KIAA0613, ZASP, LIM domain-binding protein 3, Protein cypher, Z-band alternatively spliced PDZ-motif protein)

Affinity Purified Purified by Protein A affinity chromatography.

LIM-domain binding factor 3

LDB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 234-262 amino acids from the Central region of human LDB3.

This gene encodes a PDZ domain-containing protein. PDZ motifs are modular protein-protein interaction domains consisting of 80-120 amino acid residues. PDZ domain-containing proteins interact with each other in cytoskeletal assembly or with other proteins involved in targeting and clustering of membrane proteins. The protein encoded by this gene interacts with alpha-actinin-2 through its N-terminal PDZ domain and with protein kinase C via its C-terminal LIM domains. The LIM domain is a cysteine-rich motif defined by 50-60 amino acids containing two zinc-binding modules. This protein also interacts with all three members of the myozenin family. Mutations in this gene have been associated with myofibrillar myopathy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been identified; all isoforms have N-terminal PDZ domains while only longer isoforms (1, 2 and 5) have C-terminal LIM domains. [provided by RefSeq].

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Polyclonal

ELISA (EL/EIA), Western Blot (WB)

Human

Anti -LDB3, ID (LDB3, KIAA0613, ZASP, LIM domain-binding protein 3, Protein cypher, Z-band alternatively spliced PDZ-motif protein)